2024 Cyclic mechanical strain

Cyclic mechanical strain

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WebThe mechanical cyclic stretch was induced by vacuum to apply 1 Hz, 10% equibiaxial strain for various time periods. 5 Three different strategies of mechanical stimulation were tested in this study, including (A) addition … WebJul 13, 2005 · Our results show that cyclic strain increased the proliferation and migration of HASM; cyclic strain increased release and activation of MMP-1, -2, and -3 and membrane type 1-MMP; MMP release was preceded by an increase in extracellular MMP inducer; Prinomastat [a MMP inhibitor (MMPI)] significantly decreased cyclic strain …

Study of Mechanical Behavior and Deformation Field …

WebThe sandstone yield strength and tensile strength were increased under cyclic loading paths by using the Brazilian splitting method. The experiment shows that (1) the sandstone specimens exhibit multiple penetrating crack damage by cyclic loading, while the tensile strength slightly increases; (2) the sandstone horizontal strain (Exx) … WebNov 1, 2005 · In the current study, we examined whether cyclic mechanical strain induced production of O 2 − in the main epithelial constituents of the lungs, airway … is cocktail a alcohol

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WebApr 2, 2024 · In the lungs, vascular endothelial cells experience cyclic mechanical strain resulting from rhythmic breathing motions and intraluminal blood pressure. Mechanical stress creates evident physiological, morphological, biochemical, and gene expression changes in vascular endothelial cells. WebThe increase of mean strain and strain amplitude intensifies the cyclic stress relaxation and cyclic softening behaviors. According to the experimental observation, a nonlinear … WebJun 25, 2010 · In nanotoxicology studies, this lung mimic revealed that cyclic mechanical strain accentuates toxic and inflammatory responses of the lung to silica nanoparticles. Mechanical strain also enhances epithelial and endothelial uptake of nanoparticulates and stimulates their transport into the underlying microvascular channel. is cocl polar

Cyclic mechanical strain induces TGFβ1-signalling in dermal

WebHeart valves are presumed to remodel their extracellular matrix upon application of mechanical strains. In this study, we investigated the effect of cyclic tensile strain on … WebSolder fatigue is the mechanical degradation of solder due to deformation under cyclic loading. This can often occur at stress levels below the yield stress of solder as a result of repeated temperature fluctuations, mechanical vibrations, or mechanical loads.Techniques to evaluate solder fatigue behavior include finite element analysis and semi-analytical … is cocktail dress semi formalWebSep 1, 2004 · Cyclic mechanical strain activates the mitogen-activated protein kinase (MAPK) pathway, promoting cell proliferation. Integrins, which act as mechanoreceptors, may activate MAPK via two major pathways, one involving focal adhesion kinase (FAK) and the other, the protein Shc. In contrast to cultured cells, exposure of intact aortas in … is coco a musical

"WebSmooth muscle tissue was engineered on two different polymeric scaffolds and subjected to cyclic mechanical strain. Short-term application of strain increased … " - Cyclic mechanical strain

Cyclic mechanical strain

WebMar 28, 2024 · Cyclic mechanical strain has been demonstrated to induce autophagy, whereas the relationship between cyclic tensile strain (CTS) and autophagy in growth plate chondrocytes (GPCs) is not clear. The objective of this study was to investigate whether CTS can regulate autophagy in GPCs in vitro and explore the potential mechanisms of … WebOct 28, 2014 · Cyclic mechanical tension was applied in a sinusoidal pattern (0.1 Hz, 24 h) with a maximal equi-biaxial increase in surface area of 10 % (similar to [28, 32] ). Cells cultured with the identical collagen suspension in the same plates, but not exposed to cyclic mechanical strain, were used as controls. Isolation of RNA and RT-PCR

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WebMay 11, 2009 · The effects of cyclic strain on VSMC migration and the mechanisms involved are poorly understood. Application of 20% strain to cultured VSMCs enhances VSMC migration (Li et al., 2003), which suggests that mechanical strain has a modulating effect on VSMC migration. Our study showed that 10% strain inhibited VSMC migration. WebSep 22, 2024 · To explore the effects of cyclic mechanical strain and soluble stimuli in regulating macrophage form and function, a uniaxial cell stretcher was used to mechanically stretch unstimulated (Unstim.), IFNγ/LPS, or IL4/IL13 stimulated BMDMs. ... Cyclic mechanical stretch not only caused differences in cell morphology, but also resulted in ...

WebSep 10, 2024 · We describe the current strategies and the mechanical properties necessary to promote a positive response in cardiac tissues from different cell sources, distinguishing between passive stimulation, which includes stiffness, topography and static stress and active stimulation, encompassing cyclic strain, compression or perfusion. WebWe have investigated the molecular mechanisms by which cyclic mechanical strain modulates myogenesis. Application of cyclic mechanical strain using the computer …

WebThe void compression stage causes porous cement mortar to present special mechanical properties. In order to study the compaction behavior and the damage evolution of the porous material, cement mortar specimens with an average porosity of 26.8% were created and cyclic uniaxial compression tests were carried out. The irreversible strain … WebCyclic mechanical strain introduced with IL-2 compromised the pulmonary barrier even further and led to a threefold increase in leakage. As expected, the addition of angiopoietin-1 stabilized the endothelial junctions and inhibited IL-2–induced vascular leakage.

WebNov 1, 2004 · Our study demonstrates that cyclic mechanical strain inhibits myogenesis through the activation of FAK, Rac-1, and NF-kappaB. Activation of NF-κB in response to cyclic stretch of C2C12 cells. A ...

WebMar 3, 2011 · Mechanical and physical properties of these materials have been studied in the past, but their stress-strain behavior in the presence of cyclic loading has … rv golf resorts flWebThe increase of mean strain and strain amplitude intensifies the cyclic stress relaxation and cyclic softening behaviors. According to the experimental observation, a nonlinear viscoelastic model is proposed to predict the mechanical behavior of butt-joints under cyclic loading, which considers the cyclic stress relaxation and cyclic softening ... is coco disney movieWebMay 5, 2024 · Cyclic mechanical strain is one of the biophysical cues that provide mechanical loading to the cells and is associated to many physiological and pathophysiological processes. For example, an appropriate regimen of mechanical loading during heart-beat is required for the cardiac cells to maintain their physiological … is coco crunch a cerealWebThe cyclic mechanical stress parameters used for our manufactured mechanical loading device ( Figures 1A,B) are as follows: 0.3 and 0.9% elastic strain magnitude, 5-Hz sinusoidal curve, for 30 min/day ( Chang et al., 2024 ). The specimen (a) with BMSCs cultured on the surface was placed into the fixed slot (b) and fixed. is coco g ratedWebJan 22, 2024 · The repeated stress, strain, force and tensile load acting in such a situation is one of the reasons why the load needed for fatigue failure is far less than the ultimate … is coco disneyWebApr 8, 2024 · This inhibition by mechanical stimulation was further confirmed using qPCR and a plaque assay, which respectively show that the application of cyclic mechanical strain leads to a 50% reduction... rv golf resorts in saskatchewanWebDec 1, 2013 · Cyclic mechanical strain effects have been investigated for numerous cell types such as endothelial cells [2], fibroblasts [3] and smooth muscle cells [4]. For … rv gooseneck kitchen faucet