The nramp family of metal-ion transporters
Splet25. avg. 2016 · Dong et al. [37] through regression analysis showed significantlynegative correlat ion between Cd Mn,implying antagonisticeffect Mnabsorption correlationbetween Cd Zn,copper (Cu) inconsistentamong leaves, stems roots.Cadmium alters exampleenzymes, transporters regulatorproteins, due itsstrong affinity car-boxylic … SpletTel +86-15010573490. ; +86-13701134610. Fax +86-10-63926370. Email [email protected]; [email protected]. Purpose: Liver cancer is the fifth most common type of cancer worldwide, and the ATP-binding cassette (ABC) transporter family has been widely accepted as a cause of multidrug resistance. This study was conducted …
The nramp family of metal-ion transporters
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Splet01. avg. 2006 · The NRAMP family includes proton-coupled metal ion transporters that mediate the transport of a broad range of metal ions, such as manganese (Mn 2+ ), Zn 2+ … SpletThe natural resistance-associated macrophage protein (Nramp) homologs form a family of proton-coupled transporters that facilitate the cellular absorption of divalent metal ions (Me2+,...
Splet10. feb. 2024 · tightly controlled and regulated. Nramps (natural resistance-associated macrophage proteins), a class of transition metal transporters present in all domains of life, regulate the levels of these divalent metal ions within cells and prevent disorders related to metal insufficiency or overload. SpletNramp1 phagocyte intracellular metal withdrawal defense. Microbes and Infections 2007 Recent progress in structure-function analyses of Nramp …
Splet19. mar. 2024 · The metal transporter CrNRAMP1 is involved in zinc and cobalt transports in Chlamydomonas reinhardtii Metal homeostasis is essential cellular progress for cell … SpletThe ubiquitous Nramp family of transport proteins, a member of the LeuT family, facilitates acquisition of metal ions, including the absorption of dietary iron in mammals. ... with M226 via a hard acid-soft base interaction. Altogether, a mechanism explaining ion selectivity of divalent metal ion membrane transporters based upon differential ...
Splet11. apr. 2024 · High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Shamayeeta Ray, Samuel P Berry, Eric A Wilson, Casey H Zhang, Mrinal Shekhar, Abhishek Singharoy, Rachelle Gaudet , Harvard University, United States; Arizona State University, United States;
Splet13. apr. 2024 · Toxic heavy metal accumulation is one of anthropogenic environmental pollutions, which poses risks to human health and ecological systems. Conventional heavy metal remediation approaches rely on expensive chemical and physical processes leading to the formation and release of other toxic waste products. Instead, microbial … payoff short callSplet11. apr. 2024 · Members of the SLC11 (NRAMP) family transport iron and other transition-metal ions across cellular membranes. These membrane proteins are present in all kingdoms of life with a high degree of ... payoff short putSplet29. avg. 2016 · The natural resistance-associated macrophage protein (Nramp) family of metal transporters represents a common transition metal acquisition strategy conserved across all kingdoms of life . The first discovered mammalian Nramp (Nramp1) is expressed in phagosomal membranes and likely extracts essential metals to help kill engulfed … scriban boisSpletNrat1 is a member of the natural resistance-associated macrophage protein (Nramp) family of metal ion transporters in all organisms. Different from other Nramp members capable of transporting divalent metals, Nrat1 specifically transports trivalent aluminum (Al) ion. However, molecular mechanism underlying the Al transport selectivity of Nrat1 remains … payoff sheetSplet25. avg. 2004 · This book is the first comprehensive volume on the "Nramp family", highlighting the physiological importance of Nramp proteins as metal transporters. The molecular knowledge of these membrane proteins is presented from an evolutionary perspective, considering Nramp cellular function and mechanism of transport in key … scriban dictionarySpletThe Natural Resistance-Associated Macrophage Protein (NRAMP) family of eukaryotic transporters was identified based on the effect of these proteins on the multiplication of intracellular pathogens. 5 Bacterial genes … payoffs myloancareSplet29. avg. 2016 · The ubiquitous Natural resistance-associated macrophage protein (Nramp) family facilitates the acquisition of these metal ions by transporting them across cellular … payoffs means