Tnpo2 foundation
WebbGene information about ENSG00000105576 / TNPO2 - transportin 2. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. WebbTransportin-2 (TNPO2) mediates multiple pathways, including nonclassical …
Tnpo2 foundation
Did you know?
WebbTNPO2 Foundation. 1401 21ST STREET SUITE 4283 SACRAMENTO, CA 95811 ... WebbExpression of TNPO2 (FLJ12155, IPO3, KPNB2B, TRN2) in liver tissue. Antibody staining with CAB046446 in immunohistochemistry. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. ... by the Knut & Alice Wallenberg Foundation. ...
WebbTNPO2 are two members of the karyopherin family of transport receptors that were implicated in a novel nuclear protein import pathway. TNPO1 and TNPO2 specifically bind to M9-containing proteins such as hnRNPA13 as well as the HNS region of HuR, but not to the classical NLS-containing proteins.4 TNPO2 (also known as TRN2, Transportin-2, WebbTNPO2 Foundation was registered on 11 May 2024 as Nonprofit Corporation - CA - Public …
WebbTransportin-2 (TNPO2) mediates multiple pathways including non-classical nucleocytoplasmic shuttling of >60 cargoes, such as developmental and neuronal proteins. We identified 15 individuals carrying de novo coding variants in TNPO2 who presented with global developmental delay (GDD), dysmorphic features, ophthalmologic abnormalities, … Webb8 dec. 2024 · TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. IPO3 binds NEMO, promotes its nuclear import, and is critical for DNA damage-dependent NF-kappaB activation. Studies indicate potential roles of Tranportin-1 and Transportin-2 beyond protein nuclear import.
WebbTNPO2 (FLJ12155, IPO3, KPNB2B, TRN2) protein expression summary. We use cookies …
Webb29 okt. 2024 · We propose that TNPO2 plays a critical role in determining the distribution of ERα between the nucleus and the cytoplasm in response to stimulation. Results Oestrogen receptor-α enters the... norm reeves irvine caWebb11 maj 2024 · TNPO2 Foundation Corporation Number: 5070709 Corporation Name: … norm reeves irvine collision centerWebb11 okt. 2024 · TNPO2 is a nuclear accessory protein, in which its transport‐assisted protein belongs to the class of RNA‐binding proteins, ... (No. 2024ZX09304025); National Natural Science Foundation of China (No. 81572374 and 31770963); Science and Technology Plan Project of Liaoning Province ... norm reeves richland hillsWebbTNPO2 Foundation 1 year 3 months Rare disease parent Feb 2024 - Present1 year 3 months Rare disease parent Feb 2024 - Present1 year 3 … norm reeves toyota irvineWebbPhenotype data for mouse gene Tnpo2. Discover Tnpo2's significant phenotypes, expression, images, histopathology and more. Data for gene Tnpo2 is all freely available for download. norm reeves hyu superstoreWebbTNPO2 is closely related to Transportin-1 ( TNPO1 [MIM: 602901]; Importin-2; Karyopherin-β2) 5 and neither gene has been associated with a Mendelian disease. TNPO2 is the less studied of the two as it was discovered later. Human TNPO2 and TNPO1 protein sequences are 84% identical and 92% similar. 5 norm reeves hyu superstore cerritosWebb8 dec. 2024 · TNPO2 variants associate with human developmental delays, neurologic … norm-referenced assessments